Leser-Trélat syndrome associated with cancer larynx : A case report

Ahmed, Mohammed; Ahmed, Mona; Abdelfattah, Hesham; Abu El-Hamd, Mohammed; Amr, Wael

doi:10.21608/ejentas.2018.10295

Leser-Trélat syndrome associated with cancer larynx : A case report

Document Type : Case report

Authors

¹ Phoniatrics, Otorhinolaryngology-Head and Neck Surgery Department, Sohag University, Sohag, Egypt

² General Otolaryngology Phoniatrics, Otorhinolaryngology-Head and Neck Surgery Department, Sohag University, Sohag, Egypt

³ Otorhinolaryngology-Head and Neck Surgery Department, University of Alexandria, Alexandria, Egypt

⁴ Dermatology, Venereology and Andrology Department, Faculty of Medicine, Sohag University

⁵ Surgery Department, Sohag Cancer Center, Sohag, Egypt

10.21608/ejentas.2018.10295

Abstract

Leser-Trélat syndrome (LTS) is a rare cutaneous paraneoplastic syndrome that barely affects patients with head and neck cancer. Here we present a case of 58-years old male presented with skin manifestation consistent with a sign of Leser-Trélat. A close investigation of the patient revealed that he had a recurrent laryngeal squamous cell carcinoma. The described case is the fifth case of a Leser-Trélat syndrome with squamous cell carcinoma of the larynx and the sixth to be reported in the head and neck squamous cell carcinoma. Thus sudden development of paraneoplastic dermatoses is recurrently a forewarning progression of the malignancy.