Elhusseiny, A., shalaby, A., Taha, H., Ahmed, O. (2022). Vestibular & Balance Assessment in Hepatitis C Virus Patients Undergoing (Sovaldi/Daklinza) Regimen. Egyptian Journal of Ear, Nose, Throat and Allied Sciences, 23(23), 1-6. doi: 10.21608/ejentas.2021.69389.1339
Aya Magdy Elhusseiny; Amany shalaby; Hesham Mohamed Taha; Ossama Ashraf Ahmed. "Vestibular & Balance Assessment in Hepatitis C Virus Patients Undergoing (Sovaldi/Daklinza) Regimen". Egyptian Journal of Ear, Nose, Throat and Allied Sciences, 23, 23, 2022, 1-6. doi: 10.21608/ejentas.2021.69389.1339
Elhusseiny, A., shalaby, A., Taha, H., Ahmed, O. (2022). 'Vestibular & Balance Assessment in Hepatitis C Virus Patients Undergoing (Sovaldi/Daklinza) Regimen', Egyptian Journal of Ear, Nose, Throat and Allied Sciences, 23(23), pp. 1-6. doi: 10.21608/ejentas.2021.69389.1339
Elhusseiny, A., shalaby, A., Taha, H., Ahmed, O. Vestibular & Balance Assessment in Hepatitis C Virus Patients Undergoing (Sovaldi/Daklinza) Regimen. Egyptian Journal of Ear, Nose, Throat and Allied Sciences, 2022; 23(23): 1-6. doi: 10.21608/ejentas.2021.69389.1339
Vestibular & Balance Assessment in Hepatitis C Virus Patients Undergoing (Sovaldi/Daklinza) Regimen
1Audiology unit
ENT department
AinShams university
2Audiology unit ENT department AinShams university
3Internal medicine, Gastroenterology & Hepatology department
Abstract
Background: Previous Hepatitis C Virus (HCV) antiviral drugs reported to cause ototoxicity. Aim: To detect any possible adverse effects of Sovaldi/ Daklinza regimen related to vestibular & balance functions. Patients and Methods: Vestibular & balance were assessed in a total number of thirty adult HCV patients , ranging from twenty to sixty years old before administration of (Sovaldi/Daklinza) and three months later , using Vestibular office tests (Head shake test, Head thrust test, Fukuda stepping test& one leg stance). Videonystagmography (VNG), Sensory organization test (SOT) of Dynamic posturagraphy. Results: After treatment, all patients had normal vestibular office tests, normal VNG testing except for three patients (10% of the study sample) showed positional nystagmus after treatment that wasn’t present before receiving Sovaldi/Daclinza & normal balance function as demonstrated by SOT of Dynamic posturagraphy, with non-statistical significant difference when comparing before and after treatment findings. Conclusion: Sovaldi/Daklinza regimen used in HCV treatment has no statistically significant effect on vestibular & balance function.
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